李志华

2008年06月10日 16:15  点击:[]

 

 

 

现为山东大学海洋学院教授,博士生导师,湖北省杰出青年基金获得者,入选武汉市青年科技晨光计划和中国水产科学研究院“百名英才”人才计划。博士毕业于捷克南波希米亚大学,长期从事水生态毒理学与环境健康风险评估研究。2010年赴美国加州大学河滨分校Prof. Danel Schlenk实验室访问交流,2011年-2012年期间,在新加坡国立大学从事博后研究。

以第一作者(或通讯)在Journal of Hazardous Materials、Water Research、Environmental Pollution等学术刊物发表,65篇(总共发表79篇),文章总被引1970次(他引1678次),H-index=27。目前担任SCI刊物Bulletin of Environmental Contamination and Toxicology的编委和Frontiers in Marine Science,Water,BioMed Research International专刊的客座主编,并担任Environmental Science & Technology等31种该领域SCI期刊的独立审稿人。申报获得授权专利11项(其中第一发明人8项)。

获得奖励包括:河北省优秀毕业生(2005);河北省优秀三好学生(2005);南波西米亚大学35岁以下青年优秀科研成果一等奖(2009);国家优秀自费留学生奖学金(2010);南波西米亚大学优秀科技成果校长奖(2011);首届中国水产青年科技奖(2016年)。

主要学术兼职包括中国水产学会青年工作委员会委员,国家自然基金通讯评审专家,教育部长江学者奖励计划通讯评审专家,科技部国际合作专项会评专家,中国水产科学研究院渔业生态学科学术委员以及湖北贵州浙江等省科技项目评审专家等。

 

学习经历

  • 1998-2002 河北大学生命科学学院 生物学 本科

  • 2002-2005 河北大学生命科学学院 水生生物学 硕士

  • 2008-2011 University of South Bohemia, Czech Republic 水生态毒理学 博士

 

工作经历

  • 2005.07-2012.12 长江水产研究所 研究实习员、助理研究员

  • 2008.10-至今 University of South Bohemia, Czech Republic Scientific Researcher

  • 20011.11-2012.11 National University of Singapore Research Fellow

  • 2013.01-2017.06 长江水产研究所 研究员

  • 2017.07-2018.05 大连理工大学环境学院 教授

  • 2018.06-至今 山东大学海洋学院 教授

 

研究兴趣:

(1)全球气候变化耦合海洋污染对近海生态环境的影响,采用典型模式物种作为实验模型,将微观与宏观相结合,在多层次水平上采用多组学交叉技术的系统毒理学方法探索气候变化背景下海洋污染的生态效应及其机制;通过构建室内微宇宙模型系统,探讨近海污染物在食物链的传递及种群效应;研究气候变化背景下近海碳循环及碳固定机制,为我国发展海洋战略、生态安全等决策提供理论依据。

(2)新兴污染物(如药物残留活性物质、人工纳米污染物等)的环境行为及其健康风险评估,主要针对水环境中新兴污染物的时空分布、来源、归趋、降解等环境行为进行调查分析,并结合室内动物模型实验分析其环境风险;筛选并验证典型污染物的敏感、有效的分子生物标记物,发展环境污染的早期预警系统,以便对污染物的环境健康风险评估提供科学依据。

(3)近岸湿地海洋牧场的养殖生态与生境调控,主要针对近海湿地海洋牧场(海水池塘)的养殖生态,水质及底质调控,以及尾水处理技术开发开展工作,为我国蓝色粮仓产业健康发展提供技术支撑。

近期主持课题情况:

  • 2018-2023, “我国重要渔业水域食物网结构特征与生物资源补充机制”项目-“重要渔业种群动态长期变化特征及生态适应性”(国家重点研发计划“蓝色粮仓科技创新”专项,2018YFD0900902,2019/01-2023/12,子课题负责人)

  • 2018-2020,环境激素三丁基锡的分子毒理学及生物标志物筛选(湖北省自然科学基金杰出青年项目,2017CFA071)

  • 2017-2019,环境激素三苯基锡内分泌干扰跨代效应研究(武汉市青年科技晨光计划,2017050304010273)

  • 2016-2019,低剂量三丁基锡与镉联合暴露对鲤鱼内分泌轴线交互影响效应及作用机制研究(国家自然科学基金,31570511)

  • 2015-2019,典型化学物污染淡水水产品质量安全综合防治技术方案(子课题)(公益性行业(农业)科研专项经费项目,201503108-CC-1)

  • 2015-2017,温度对草鱼幼鱼在低剂量汞胁迫下毒代动力学及生理应答影响研究(国家自然科学基金,21407181)

  • 2015-2016,不同温度下草鱼幼鱼对汞胁迫的耐受性研究(湖北省自然科学基金面上项目,2014CFB266)

  • 2014-2016,环境激素三丁基锡对鲤鱼的危害及其机制(中国水产科学研究院基本科研业务费,2014A02YQ01)

  • 2013-2014,三峡库区水体中典型环境激素有机锡化合物的生态毒理学研究(农业部留学人员科技活动择优资助项目)

  • 2013-2015,气体过饱和、重金属和典型有机污染物对鱼类等水生生物影响机理研究(三峡总公司课题-重金属部分,07011034)

  • 2012-2014,-利用被动采样/质谱技术对长江流域新型污染物的检测及鉴定(中捷政府间科技合作项目,LH12179)

    获奖情况:

  • 2005,河北省优秀毕业生;河北省优秀三好学生;

  • 2009,南波西米亚大学渔业与水保护学院35岁以下青年优秀科研成果一等奖;

  • 2010,国家优秀自费留学生奖学金;

  • 2011,南波西米亚大学优秀科技成果校长奖。

  • 2016,中国水产青年科技奖。

     

    学术兼职

  • SCI刊物编辑:Bulletin of Environmental Contamination and Toxicology

  • SCI刊物特约主编:Frontiers in Marine Science专刊“Influences of Climate Change Coupled with Aquatic Pollutions”.

  • SCI刊物特约主编:Water专刊“Effects of Emerging Pollutants on Ecological Health in Aquatic Environment”.

  • SCI刊物特约主编:BioMed Research International专刊“Endocrine Toxicology in Aquatic System”、“Aquatic Environment Health and Toxicology”.

  • SCI刊物独立审稿人:Water Research, Journal of Hazardous Materials, Environmental Science & Technology, Environmental Pollution, Science of the Total Environment, Chemosphere, BMC Veterinary Research, Comparative Biochemistry and Physiology-Part B, Part C, Environmental Toxicology and Chemistry, Mutation Research, Ecotoxicology and Environmental Safety, Environmental Toxicology, Experimental and Molecular Pathology, Marine Environmental Research, Aquaculture Nutrition, Food and Chemical Toxicology, PLoS ONE, Diseases of Aquatic Organisms, Journal of Environmental Management, Fish Physiology and Biochemistry, Bulletin of Environmental Contamination and Toxicology, Aquaculture research, Reproductive Biology.

  • 中国水产学会青年工作委员会委员,国家自然基金通信评审专家,科技部国际合作专项会评专家,教育部长江学者奖励计划通信评审专家,科技部创新人才推进计划通信评审专家,中国水产科学研究院渔业生态学科学术委员以及广东湖北贵州浙江等省科技项目评审专家等。

发表SCI文章情况

 

  • Total number of publication with the first/corresponding author:65

  • Sum of the Times Cited:1870 (1578 without self-citation)

  • H-index:27

 

As the first author or corresponding author

 

  1. He, S.W., Yu, D.D., Li, P., Zhang, M., Xing, S.Y., Sun, C.C,Li, Z.H.*2021. Triphenyltin exposure causes changes in the health-associated gut microbiome and metabolites in marine medaka.Environmental Pollution, 288,117751.

  2. Zhang, S.Q.1, Li, P.1, Zhao, X.L., He, S.W., Xing, S.Y., Cao, Z.H., Zhang, H.Q.*,Li, Z.H.*2021. Hepatotoxicity in carp (Cyprinus carpio) exposed to environmental levels of norfloxacin (NOR): Some latest evidences from transcriptomics analysis, biochemical parameters and histopathological changes. Chemosphere, 283, 131210.

  3. Zhao, X.L.1, Li, P.1, Zhang, S.Q., He, S.W., Xing, S.Y., Cao, Z.H., Lu, R.,Li, Z.H.*2021. Effects of environmental norfloxacin concentrations on the intestinal health and function of juvenile common carp and potential risk to humans. Environmental Pollution, 287, 117612.

  4. Li Z.H*.,Li P.*, Wu Y.H. 2021. Effects of temperature fluctuation on endocrine disturbance of grass carpCtenopharyngodon idellaunder mercury chloride stress. Chemosphere, 263, 128137.

  5. Li, Z.H.*,Li, P*.2021. Effects of the tributyltin on the blood parameters, immune responses and thyroid hormone system in zebrafish.Environmental Pollution, 268, 115707.

  6. Li Z.H*.,Li P.*, Wu Y.H. 2021. Regulation of glutathione-dependent antioxidant defense system of fish Ctenopharyngodon idella under the combined stress of mercury and temperature.Environmental Science and Pollution Research,28, 1689–1696.

  7. He, S.W., Li, P.,Li, Z.H.*.2021. Review on endocrine disrupting toxicity of triphenyltin from the perspective of species evolution: Aquatic, amphibious and mammalian. Chemosphere,269, 128711.

  8. Zhang, S.Q., Li, P.,Li, Z.H.*2021.Toxicity of organotin compounds and the ecological risk of organic tin with co-existing contaminants in aquatic organisms. Comp Biochem Physiol C Toxicol Pharmacol 246, 109054.

  9. Li, Z.H.,Li, Z.P., Tang, X., Hou, W.H., Li, P*. 2021. Distribution and risk assessment of toxic pollutants in surface water of the lower Yellow river, China. Water, 13, 1582.

  10. Li, P.,Li, Z.H.*.2021. Neurotoxicity and physiological stress in brain of zebrafish chronically exposed to tributyltin. Journal of Toxicology and Environmental Health, Part A Current Issues, 84, 20-30.

  11. Li P.,Li Z.H.*,Wu Y.H. 2021. Interactive effects of temperature and mercury exposure on the stress-related responses in the freshwater fish Ctenopharyngodon idella. Aquaculture Research. 52, 2070–2077.

  12. Li Z.H.*,Li P., Wu Y.H. 2021. Effects of waterborne mercury at different temperature on hematology and energy metabolism in grass carp (Ctenopharyngodon idella).International Journal of Environmental Science and Technology,18, 1489–1498.

  13. Li, P.,Li, Z.H.*.2020. Tributyltin induces the tissue-specific stresses in zebrafish, a study in various tissues of muscle, gill and intestine. Bulletin of Environmental Contamination and Toxicology,105, 847–852.

  14. Li, P.,Li, Z.H.*.2020.Toxicity evaluation of triphenyltin in zebrafish larvae by embryonic malformation, retinal development, and GH/IGF axis.Fish Physiology and Biochemistry,46, 2101-2107

  15. Li, P.,Li, Z.H.*. 2020. Environmental co-exposure to TBT and Cd caused neurotoxicity and thyroid endocrine disruption in zebrafish, a three-generation study in a simulated environment. Environmental Pollution, 259,113868.

  16. Li, P.,Li, Z.H.*,Zhong L.Q. 2020. Parental exposure to triphenyltin inhibits growth and disrupts thyroid function in zebrafish larvae. Chemosphere, 240,124936.

  17. Li, P.,Li, Z.H.*,Zhong L.Q. 2019. Effects of low concentrations of triphenyltin on neurobehavior and the thyroid endocrine system in zebrafish. Ecotoxicology and Environmental Safety,186,109776.

  18. Li, P.,Li, Z.H.*,Zhong, L.Q. 2019. Triphenyltin exposure alters the antioxidant system, energy metabolism and the expression of genes related to physiological stress in zebrafish (Danio rerio). Comp Biochem Physiol C Toxicol Pharmacol 225, 108581.

  19. Li Z.H*.,Li P.*, Shi Z.C. 2016.Chronic effects of tributyltin on multiple biomarkers responses in juvenile common carp,Cyprinus carpio.Environmental Toxicology, 31(8):937-944.

  20. Li Z.H*.,Zhong L.Q., Mu W.N. Wu Y.H. 2016.Effects of chronic exposure to tributyltin on tissue-specific cytochrome P450 1 regulation in juvenile common carp.Xenobiotica. 46(6):511-515.

  21. Li Z.H*.,Li P., Shi Z.C. 2016.Physiological and molecular responses in brain of juvenile common carp (Cyprinus carpio) following exposure to tributyltin.Environmental Toxicology,31(3):278-284.

  22. Li Z.H*.,Zhong L.Q., Mu W.N. Wu Y.H. 2016.Toxicity of tributyltin in juvenile common carp (Cyprinus carpio): physiological responses, hepatic gene expression and stress protein profiling.Journal of Biochemical and Molecular Toxicology, 30(2):91-96.

  23. Li Z.H*.,Zhong L.Q., Mu W.N. Wu Y.H. 2016.Alteration of cytochrome P450 1 regulation and HSP 70 level in brain of juvenile common carp (Cyprinus carpio) after chronic exposure to tributyltin.Fish Physiology and Biochemistry, 42(1):287-294.

  24. Li Z.H*.,He K., Liu C., Li P., Zlabek V., 2016. Aquatic Environmental Health and Toxicology.BioMed Research International, 2016 (2016), Article ID 3514898.

  25. Li Z.H*.,Zhong L.Q., Mu W.N. Wu Y.H. 2016.Alteration of parameters of energy metabolism and ATPase enzymatic system in juvenile common carp (Cyprinus carpio) chronically exposed to tributyltin, Czech Journal of Animal Science, 61(7):326-332.

  26. Wu Y.H,Li Z.H*.,Zhong L.Q. Chen D.Q. 2016.Tissue-specific stress and hepatic DNA damage inPelteobagrus fulvidracocaused by low concentrations of cadmium. Toxicological & Environmental Chemistry. 98(1):90-100.

  27. Mu W.N,Li Z.H*.,Zhong L.Q. Wu Y.H. 2016 Effect of tributyltin, cadmium and their mixture on physiological responses in juvenile grass carp,Ctenopharyngodon idella, Journal of Aquatic Animal Health, 28(3):181-186.

  28. Li Z.H*.,Wu Y.H., Li P., Li Y.F., Ni Z.H. 2015.Alterationof antioxidant response and expression of related genes by Cadmium in Chinese rare minnow larvae.CLEAN - Soil, Air, Water, 43(5), 671–675

  29. Li Z.H*.,Li P., Shi Z.C.2015.Chronic exposure to tributyltin induces brain functional damage in juvenile common carp (Cyprinus carpio) PLoS ONE, 10(4), e0123091.

  30. Li Z.H*.,Li P.,& Shi Z.C. 2015.Responses of the hepatic glutathione antioxidant defense system and related gene expression in juvenile common carp after chronic treatment with tributyltin. Ecotoxicology,24, 700-705.

  31. Li, Z.H*.,Li, P. 2015. Evaluation of tributyltin toxicity in Chinese rare minnow larvae by abnormal behavior, energy metabolism and endoplasmic reticulum stress.Chemico-Biological Interactions,227, 32–36

  32. Li P. Li Z.H*.2015.Physiological responses in Chinese rare minnow larvae following exposure to low-dose tributyltin. Bulletin of Environmental Contamination and Toxicology,95:588–592.

  33. Li, P.*,Li, Z.H.*, Hulak, M., Rodina, M., Linhart, O., 2012. Regulation of spermatozoa motility in response to cations in Russian sturgeon (Acipenser gueldenstaedtii). Theriogenology 78(1): 102-109(* corresponding author)

  34. Li, Z.H*.,Li, P., Chen, L., 2014. Temperature affects Hg-induced antioxidant responses in Chinese rare minnowGobiocypris raruslarvae in vitro. Bulletin of Environmental Contamination and Toxicology,93, 666-669.

  35. Li Z.H*.,Li P., Shi Z.C. 2014. Molecular responses in digestive tract of juvenile common carp after chronic exposure to sublethal tributyltin. Ecotoxicology and Environmental Safety, 109, 10-14.

  36. Li Z.H*.,Chen L., Wu Y.H., Li P., Li Y.F., Ni Z.H.*2014. Effects of mercury on oxidative stress and gene expression of potential biomarkers in larvae of the Chinese rare minnowGobiocypris Rarus. Archives of Environmental Contamination and Toxicology, 67, 245-251.

  37. Li Z.H*.,Chen L., Wu Y.H., Li P., Li Y.F., Ni Z.H.* 2014. Alteration of thyroid hormone levels and related gene expression in Chinese rare minnow larvae exposed to mercury chloride. Environmental Toxicology and Pharmacology, 38, 325-331.

  38. Li Z.H*.,Chen L., Wu Y.H., Li P., Li Y.F., Ni Z.H.* 2014. Effects of waterborne cadmium on thyroid hormone levels and related gene expression in Chinese rare minnow larvae. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 161, 53-57.

  39. Li, Z.H.,Xu, H.Y., Zheng, W.L., Lam, S.H., Gong, Z.Y*. 2013. RNA-sequencing analysis of TCDD-induced responses in zebrafish liver reveals high relatedness to in vivo mammalian models and conserved biological pathways. PLoS ONE, 8(10): e77292.

  40. Li, Z.H.*, Zlabek, V., Velisek, J., Grabic, R., Machova, J., Kolarova, J., Li, P., Randak, T. 2013. Multiple biomarkers responses in juvenile rainbow trout,Oncorhynchus mykiss, after acute exposure to a fungicide propiconazole. Environmental Toxicology 28(3):119-126.

  41. Li, Z.H.*, Li, P.*, Sulc, M., Hulak, M., Randak, T.,2012.Hepatic proteome sensitivity in rainbow trout after chronically exposed to a human pharmaceutical Verapamil. Molecular and Cellular Proteomics, 11(1):M111.008409.

  42. Li Z.H.*,Li P., Randak T. 2011. Protective roles of calcium channel blocker against cadmium-induced physiological stress in freshwater teleostOncorhynchus mykiss. Water, Air, & Soil Pollution 220 (1-4):293-299.

  43. Li, Z.H.*,Li, P., Randak, T. 2011. Evaluating the toxicity of environmental concentrations of waterborne chromium (VI) to a model teleost,Oncorhynchus mykiss: a comparative study of in vivo and in vitro. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 153(4): 402-407.

  44. Li Z.H.*,Velisek J., Grabic R., Li P., Kolarova J., Randak T. 2011. Use of hematological and plasma biochemical parameters to assess the chronic effects of a fungicide Propiconazole on a freshwater teleost. Chemosphere, 83(4): 572-578.

  45. Li, Z.H.*,Zlabek, V., Li, P., Grabic, R., Velisek, J., Machova, J., Randak, T., 2011. Acute toxicity of carbamazepine to juvenile rainbow trout (Oncorhynchus mykiss): effects on antioxidant responses, hematological parameters and hepatic EROD. Ecotoxicology and Environmental Safety

    74 (3): 319-327.

  46. Li, Z.H.*,Zlabek, V., Grabic, R., Li, P.,Randak, T., 2011. Biochemical responses in gill of rainbow trout exposed to propiconazole. Central European Journal of Biology 6 (1): 84-90.

  47. Li, Z.H.*,Velisek, J., Zlabek, V., Grabic, R., Machova, J., Kolarova, J., Li, P., Randak, T., 2011. Chronic toxicity of Verapamil on juvenile rainbow trout (Oncorhynchus mykiss): effects on morphological indices; hematological parameters and antioxidant responses. Journal of HazardousMaterials 185 (2-3): 870-880.

  48. Li, Z.H.*,Zlabek, V., Velisek, J., Grabic, R., Machova, J.,Kolarova, J., Li, P.,Randak, T., 2011. Antioxidant responses and plasma biochemical characteristics in the freshwater rainbow trout,Oncorhynchus mykiss, after acute exposure to the fungicide propiconazole. Czech Journal of Animal Science56(2):64-72.

  49. Li, Z.H.*,Zlabek, V., Turek, J., Velisek, J., Pulkrabova, J., Kolarova, J., Sudova, E., Berankova, P., Hradkova, P., Hajslova, J., Randak, T., 2011. Evaluating environmental impact of STPs situated on streams in the Czech Republic: An integrated approach to biomonitoring the aquatic environment. Water Research 45 (3): 1403-1413.

  50. Li, Z.H.*,Li, P., Dzyuba, B., Randak, T., 2010. Influence of environmental related concentrations of heavy metals on motility parameters and antioxidant responses in sturgeon sperm. Chemico-Biological Interactions188(3): 473-477.

  51. Li, Z.H.*,Li, P, Rodina, M, Randak, T., 2010. Evaluating the function of calcium antagonist on the cadmium-induced stress in sperm of Russian sturgeon,Acipenser gueldenstaedtii.Aquatic Toxicology100(4):373-375.

  52. Li, Z.H.*,Li, P., Randak, T., 2010. Effect of a human pharmaceutical carbamazepine on antioxidant responses in brain of a model teleostin vitro: An efficient approach to biomonitoring. Journal of Applied Toxicology 30(7):644-648.

  53. Li, Z.H.*,Li, P., Randak, T., 2010. Ecotoxocological effects of short-term exposure to a human pharmaceutical Verapamil in juvenile rainbow trout (Oncorhynchus mykiss). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology152(3): 385-391.

  54. Li, Z.H.*,Zlabek, V., Grabic, R., Li, P., Randak, T., 2010. Modulation of glutathione-related antioxidant defense system of fish, chronically treated by the fungicide propiconazole. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology152(3):392-398.

  55. Li, Z.H.*,Zlabek, V., Li, P., Grabic, R., Velisek, J., Machova, J., Randak, T., 2010. Biochemical and physiological responses in liver and muscle of rainbow trout after long-term exposure to propiconazole. Ecotoxicology and Environmental Safety73(6): 1391-1396.

  56. Li, Z.H.*,Zlabek, V., Grabic, R., Li, P., Machova, J., Velisek, J., Randak, T., 2010. Effects of exposure to sublethal propiconazole on the antioxidant defense system and Na+-K+-ATPase activity in brain of rainbow trout,Oncorhynchus mykiss. Aquatic Toxicology 98(3): 297-303.

  57. Li, Z.H.*,Li, P, Rodina, M, Randak, T., 2010. Effect of human pharmaceutical Carbamazepine on the quality parameters and oxidative stress in common carp (Cyprinus carpioL.) spermatozoa. Chemosphere 80(5): 530-534.

  58. Li, Z.H.*,Velisek, J., Zlabek, V., Grabic, R., Machova, J., Randak, T., 2010. Enzymatic alterations and RNA/DNA ratio in intestine of rainbow trout,Oncorhynchus mykiss, induced by chronic exposure to carbamazepine. Ecotoxicology 19(5): 872–878.

  59. Li, Z.H.*,Zlabek, V., Grabic, R., Li, P., Machova, J., Velisek, J., Randak, T., 2010. Effects of exposure to sublethal propiconazole on intestine-related biochemical responses in rainbow trout,Oncorhynchus mykiss. Chemico-Biological Interactions 185(3): 241-246.

  60. Li, Z.H.*,Zlabek, V., Velisek, J., Grabic, R., Machova, J., Randak, T., 2010. Physiological condition status and muscle-based biochemical responses in rainbow trout (Oncorhynchus mykiss), after long-term exposure to carbamazepine. Journal of Applied Toxicology 30(3): 197-203.

  61. Li, Z.H.*,Velisek, J., Zlabek, V., Grabic, R., Machova, J., Kolarova, J., Randak, T., 2010. Hepatic antioxidant status and haematological parameters in rainbow trout,Oncorhynchus mykiss, after chronic exposure to carbamazepine. Chemico-Biological Interactions 183(1): 98-104.

  62. Li, Z.H.*,Zlabek, V., Velisek, J., Grabic, R., Machova, J., Randak, T., 2010. Modulation of antioxidant defence system in brain of rainbow trout (Oncorhynchus mykiss) after chronic carbamazepine treatment. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 151(1): 137-141.

  63. Li, Z.H.*,Zlabek, V., Velisek, J., Grabic, R., Machova, J., Randak, T., 2009. Responses of antioxidant status and Na+-K+-ATPase activity in gill of rainbow trout,Oncorhynchus mykiss, chronically treated with carbamazepine. Chemosphere 77(11):1476-1481.

  64. Li, Z.H.,Xie, S., Wang, J.X., Sales, J., Li, P., Chen, D.Q.*, 2009. Effect of intermittent starvation on growth and some antioxidant indexes ofMacrobrachium nipponense(De Haan). Aquaculture research 40(5): 526-532.

  65. Li, Z.H.*,Randak, T., 2009. Residual pharmaceutically active compounds (PhACs) in aquatic environment: status, toxicity and kinetics.Veterinarni Medicina52 (7): 295-314.

As co-auhor

  1. Lui E.Y., Li C.,Li Z.H.,Gong Z., Lam S.H. 2016 Molecular insights of organochlorine biocide-induced toxicity in zebrafish: Whole-adult-organism toxicogenomics, targeted gene expression and histological analyses. Journal of Genetics and Genomics 43(8):525-528.

  2. Velisek, J*, Svobodova, Z, Kouba, A,Li, Z.H.2014 .Fish and Crayfish Toxicology.BioMed Research International, Article Number: 768689

  3. Lam, S.H., Ung. C.Y., Hlainga, M.M., Hu, J.,Li, Z.H.,Mathavanc, S., Gong, Z.Y*. 2013.Molecular insights into 4-nitrophenol-induced hepatotoxicity in zebrafish: Transcriptomic, histological and targeted gene expression analyses.Biochimica et Biophysica Acta (BBA) - General Subjects 1830(10): 4778–4789

  4. Li, P., Hulak, M.,Li, Z.H.,Sulc, M., Psenicka, M., Rodina, M., Gela, D., Linhart, O. 2013. Cryopreservation of common carp (Cyprinus carpioL.) sperm induces protein phosphorylation in tyrosine and threonine residues.Theriogenology80(2): 84-89.

  5. Burkina, V., Zamaratskaia, G., Randak, T.,Li, Z.H.,Fedorova, G., Pickova, G., Zlabek, V., 2012.Verapamil does not modify catalytic activity of CYP450 in rainbow trout after long-term exposure.Ecotoxicology and Environmental Safety79(1): 148-152.

  6. Li, P., Rodina, M, Hulak, M.,Li, Z.H.,Linhart, O., 2011. Spermatozoa concentration, seminal plasma composition and their physiological relationship in the endangered stellate sturgeon (Acipenser stellatus) and Russian sturgeon (Acipenser gueldenstaedtii). Reproduction in Domestic Animals46(2):247–252.

  7. Li, P., Rodina, M., Hulak, M., Gela, D., Psenicka, M.,Li, Z.H.,Linhart, O., 2011. Physico-chemical properties and protein profiles of sperm from three freshwater chondrostean species: a comparative study among Siberian sturgeon (Acipenser baerii), sterlet (Acipenser ruthenus) and paddlefish (Polyodon spathula).Journal of Applied Ichthyology 27(2):673–677.

  8. Velisek, J., Stara, A.,Li, Z.H.,Silovska, S., Turek, J. 2011. Comparison of the effects of four anaesthetics on biochemical bloodprofile and oxidative stress biomarkers of rainbow trout. Aquaculture 310 (3-4): 369-375.

  9. Li, P., Hulak, M., Rodina, M.,Sulc, M.,Li, Z.H.,Linhart, O.,2010. Comparative protein profiles: potential molecular markers from spermatozoa of Acipenseriformes (Chondrostei, Pisces).Comparative Biochemistry and Physiology: Part D: Genomics and Proteomics5(4): 302-307.

  10. Li, P.,Li, Z.H.,Dzyuba, B., Hulak, M., Rodina, M., Linhart, O.,2010.Evaluating the impacts of osmotic and oxidative stress on common carp(Cyprinus carpio, L.) sperm caused by cryopreservation techniques. Biology of Reproduction83(5): 852-858.

  11. Li, P., Dzyuba, B., Hulak, M., Rodina, M., Boryshpolets, S.,Li, Z.H.,Linhart, O., 2010. Percoll gradient separation of cryopreserved common carp spermatozoa to obtain a fraction with higher motility, velocity and membrane integrity. Theriogenology74(8): 1356-1361.

  12. Li, P., Rodina, M.,Hulak, M.,Gela, D.,Li, Z.H.,Linhart, O.,2010. Physico-biochemical parameters and protein profiles of sperm from belugaHuso huso. Journal of Applied Ichthyology 26(5): 753-755.

  13. Duan, X.B., Liu, S.P., Huang, M.G., Qiu, S.L.,Li, Z.H.,Wang, K., Chen, D.Q., 2009.Changes in abundance of larvae of the four domestic Chinese carps in the middle reach of theYangtze River, China, before and after closing of the Three Gorges Dam. EnvironmentalBiologyofFishes86(1):13-22.

  14. Wang, W.N., Wang, A.L., Zhang, Y.J.,Li, Z.H.,Wang, J.X., Sun, R.Y. 2004.Effects of nitrite on lethal and immune response ofMacrobrachium nipponense.Aquaculture 232 (1-4): 679-686.

 

International conferences

Li, Z.H., Li, P., Rodina, M., Randak, T., 2011.Could calcium antagonist protect sturgeon sperm from Cd-induced stress?In: Book of abstracts from 3rdInternational Workshop on the Biology of Fish Gametes. 7-9 September 2011, Budapest, Hungary. pp 136-137.

Li, P.,Li, Z.H., Dzyuba, B., Hulak, M., Rodina, M., Linhart, O., 2011.Oxidative stress induced by cryopreservation on common carp sperm. In: Book of abstracts from 3rdInternational Workshop on the Biology of Fish Gametes. 7-9 September 2011, Budapest, Hungary. pp 36-37.

Li, Z.H.,Zlabek, V., Velisek, J., Grabic, R., Machova, J., Kolarova, J., Randak, T., 2010. Responses of multiple biomarkers in juvenile rainbow trout,Oncorhynchus mykiss, after acute exposure to a human pharmaceutical carpamazepine. In: Abstracts of the XII International Congress of Toxicology, Barcelona, Spain. Toxicology Letters 196,Supplement 1: S116.

Li, Z.H.,Randak, T., 2009. Ecotoxicological effects of pharmaceuticals present in the aquatic environment. 14th Interdisciplinary Toxicology Conference. Brno, Czech Republic, from 1st to 3rd Jun, 2009.

Li, Z.H.,Velisek, J., Zlabek, V., Grabic, R., Machova, J., Kolarova, J., Randak, T., 2009. Antioxidant responses and plasma biochemical characteristics in the freshwater rainbow trout, Oncorhynchus mykiss, after acute exposure to the fungicide propiconazole. In: Abstracts of the 11th Interdisciplinary Toxicology Conference, TOXCON 2009, Brno, Interdisciplinary Toxicology, 2: 120.

授权专利情况:

  1. 李志华;武艳华;钟利桥。一种水流胁迫下研究鱼类行为的实验装置,ZL201510186067.3,国家知识产权局,发明专利,2017年9月15日

  2. 李志华;武艳华;钟利桥。一种小型水生生物补偿生长代谢行为在线监测装置,ZL201510621783.X,国家知识产权局,发明专利,2018年4月10日

  3. 李志华;陈露;武艳华。一种鱼类实验中测定捕食胁迫的装置,ZL201320530584.4,国家知识产权局,实用新型专利,2014年3月12日

  4. 李志华;武艳华;陈露。一种生物样品取样装置,ZL201320531559.8,国家知识产权局,实用新型专利,2014年3月12日

  5. 李志华;陈露;武艳华。一种鱼类形态学指标测定装置ZL201320500778.X国家知识产权局,实用新型专利,2014年3月12日

  6. 李志华;陈露;武艳华。一种野外小型水生生物样品采集箱,ZL201320570596.X,国家知识产权局,实用新型专利,2014年4月16日

  7. 李志华;武艳华;陈露。一种多层实验用PE手套,ZL201320668098.9,国家知识产权局,实用新型专利,2014年4月16日

  8. 李志华;陈露;武艳华。一种水生态毒理实验毒物浓度控制系统,ZL201320891104.7,国家知识产权局,实用新型专利,2014年10月1日

  9. 武艳华;李志华;钟利桥。一种组合式手套,ZL201520238721.6, 国家知识产权局,实用新型专利,2015年8月19日

  10. 武艳华;李志华;钟利桥。一种新型注射器,ZL201520236516.6,国家知识产权局,实用新型专利,2015年9月2日

  11. 木伟娜;李志华;钟利桥;刘伟。一种方便获取钢珠、玻璃珠的装置,ZL201621326208.3,国家知识产权局,实用新型专利,2017年6月30日


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