厉萍

2002年07月10日 16:20  点击:[]

193C9

厉萍,中共党员,现就任于山东大学(威海)海洋学院,副研究员,硕士生导师。主要从事低温冷冻生物学、蛋白组学和细胞生物学以及环境生物学方面研究。近期,主持国家自然基金青年项目1项,主持捷克自然基金1项,主持中央院所基本科研业务费1项,参加行业专项、973项目等多项课题。目前为止,发表SCI论文50余篇,其中第一作者(或通讯作者)19篇,参编中英文专著4部,获得授权发明专利3项。2015年获第三批“中国水产科学研究院百名科技英才培育计划”人选。此外,还担任BioMed Research International专刊客座编辑,以及PloS ONE; BioMed Research International; Reproduction, Fertility and Development; Fish Physiology and Biochemistry等SCI期刊的独立审稿人。

邮箱:liping2018@email.sdu.edu.cn

教育工作经历

Ø 2004年7月毕业于山东师范大学生命科学学院,获学士学位。

Ø 2007年7月获华中农业大学水产学院湿地资源与环境专业硕士学位。

Ø 2007年10月至2011年10月赴捷克南波希米亚大学水产养殖与水保护学院从事鱼类精液超低温冷冻保存技术及精子冷冻损伤机制研究,并获得博士学位;曾赴日本筑波大学下田海洋研究中心实验室访问交流(2009年1-4月);在捷克获得由国家留学基金委颁发的2010年度国家优秀自费留学生奖学金。

Ø 2011年11月至2012年11月赴新加坡国立大学生物系从事博士后研究工作,主要运用代谢组学和iTRAQ标记的蛋白质组学研究水体污染物对鱼类影响的分子机制。

Ø 2007年7月至2018年4月任职于中国水产科学研究院长江水产研究所。

Ø 2018年5月至今 山东大学(威海),海洋学院。

主持课题情况

· 国家自然基金青年项目,鲟鱼精子质量蛋白质标志物的筛选与功能研究(31402301),2015/01-2017/12,24万元。

· GACR 16-02407Y Tf in the seminal plasma of carp and some sturgeons can help us to identify the role of proteins in the freezing of sperm (Projects supported by Czech Science Foundation 2016-2018, leader Ping Li),5985000CZK。

· 中央级公益性科研院所基本科研业务费,水产生物生殖调控相关机制及技术研究-达氏鲟精原干细胞体外增殖与冷冻保存(2015B02YQ01),2015/01- 2017/12,28万元。

· 072/2008/P Ice-age endurance: difference expressions of sperm proteins before and after cryopreservation in teleost fishes (Projects supported by Grant agency of University of South Bohemia 2009, leader Ping Li)。

· 003/2010/Z Effect of cryopreservation on phosphorylation state of sperm proteins of common carp, Cyprinus carpio L. (Projects supported by Grant agency of University of South Bohemia 2010, leader Ping Li)。

已发表SCI文章列表:

[1]. Li P.,Guo W., Qiao X.M., Liu Z.G.,Shen L.,Wei Q.W.*,2018.Morphology and ultrastructure of Dabry’s sturgeon (Acipenser dabryanus) spermatozoa using scanning and transmission electron microscopy. Journal of Applied Ichthyology. Accepted.

[2]. Xi M.D.#,Li P.#, Du H., Qiao X.M., Liu Z.G., Wei Q.W.*,2018.Disaccharidecombinations and theexpression ofenolase3 (ENO3) andplasmamembrane Ca2+ ATPaseisoform (PMCA2) insturgeonspermcryopreservation. Reproduction inDomesticAnimals.53: 472-483.

[3]. Li P., Xi M.D., Du H., Qiao X.M., Liu Z.G., Wei Q.W.* 2018.Antioxidant supplementation, effect on post-thaw spermatozoon function in three sturgeon species.Reproduction in Domestic Animals.53: 287-295.

[4]. Li P., Guo W., Yue H.M., Li C.J., Du H., Qiao X.M., Liu Z.G., Zhou Q., Wei Q.W. *.2017. Variability in the protein profiles in spermatozoa of two sturgeon species.PLoS One. 12(10): e0186003.

[5]. Li, P.*, Hulak, M., Li, Z.H., Sulc, M., Psenicka, M., Rodina, M., Gela, D., Linhart., O., 2013.Cryopreservation of common carp (Cyprinus carpio L.) sperm induces protein phosphorylation in tyrosine and threonine residues.Theriogenology, 80(2): 84-89.

[6]. Li, P.*, Li, Z.H.*, Hulak, M., Rodina, M., Linhart, O., 2012.Regulation of spermatozoa motility in response to cations in Russian sturgeon (Acipenser gueldenstaedtii). Theriogenology 78(1):102-109.

[7]. Li, P.*, Rodina, M., Hulak, M., Li, Z.H., Linhart, O., 2011.Spermatozoa concentration, seminal plasma composition and their physiological relationship in the endangered stellate sturgeon (Acipenser stellatus) and Russian sturgeon (Acipenser gueldenstaedtii). Reproduction in Domestic Animals 46(2): 247-252.

[8]. Li, P.*, Rodina, M., Hulak, M., Gela, D., Psenicka, M., Li, Z.H., Linhart, O., 2011.Physico-chemical properties and protein profiles of sperm from three freshwater chondrostean species: a comparative study among Siberian sturgeon (Acipenser baerii), sterlet (Acipenser ruthenus) and paddlefish (Polyodon spathula). Journal of Applied Ichthyology 27(2): 673-677.

[9]. Li, P.*, Li, Z.H., Dzyuba, B., Hulak, M., Rodina, M., Linhart, O., 2010. Evaluating the impacts of osmotic and oxidative stress on common carp (Cyprinus carpio, L.) sperm caused by cryopreservation techniques.Biology of Reproduction 83(5): 852-858.

[10]. Li, P.*, Dzyuba, B., Hulak, M., Rodina, M., Boryshpolets, S., Li, Z.H., Linhart, O., 2010. Percoll gradient separation of cryopreserved common carp spermatozoa to obtain a fraction with higher motility, velocity and membrane integrity. Theriogenology, 74(8): 1356-1361.

[11]. Li, P.*, Hulak, M., Koubek, P., Sulc, M., Dzyuba, B., Boryshpolets, S., Rodina, M., Gela, D., Manaskova-Postlerova, P., Peknicova, J., Linhart., O., 2010. Ice-age endurance: the effects of cryopreservation on proteins of sperm of common carp,Cyprinus carpio L. Theriogenology 74(3): 413-423.

[12]. Li, P.*, Hulak, M., Rodina, M., Sulc, M., Li, Z.H., Linhart, O., 2010.Comparative protein profiles: potential molecular markers from spermatozoa of Acipenseriformes (Chondrostei, Pisces).Comparative Biochemistry and Physiology: Part D: Genomics and Proteomics 5(4): 302-307.

[13]. Li, P.*, Rodina, M., Hulak, M., Gela, D., Li, Z.H., Linhart, O., 2010.Physico-biochemical parameters and protein profiles of sperm from belugaHuso huso. Journal of Applied Ichthyology 26(5): 753-755.

[14]. Li, P., Hulak, M., Linhart, O., 2009.Sperm proteins in teleostean and chondrostean (sturgeon) fishes. Fish Physiology and Biochemistry 35(4):567-581.

[15]. Li, P., Wei, Q., Liu, L., 2008. DNA integrity of Polyodon spathula cryopreserved sperm. Journal of Applied Ichthyology 24(2): 121-125.

[16]. Li, Z.H.*,Li, P.*, Sulc, M., Hulak, M., Randak, T.,2012.Hepatic proteome sensitivity in rainbow trout after chronically exposed to a human pharmaceutical Verapamil. Molecular and Cellular Proteomics, 11(1):M111.008409.

[17]. Li P.& Li Z.H*. 2015. Physiological responses in Chinese rare minnow larvae following exposure to low-dose tributyltin. Bulletin of Environmental Contamination and Toxicology, 95:588–592.

[18]. Li Z.H.*,Li P.*, Shi Z.C. 2015.Responses of the hepatic glutathione antioxidant defense system and related gene expression in juvenile common carp after chronic treatment with tributyltin. Ecotoxicology, 24, 700-705.

[19]. Li Z.H.*,Li P.*, Shi Z.C. 2016. Chronic effects of tributyltin on multiple biomarkers responses in juvenile common carp,Cyprinus carpio. Environmental Toxicology. 31(8),937-944.

[20]. Li Z.H.*,Li P.*, Shi Z.C. 2016.Physiological and molecular responses in brain of juvenile common carp (Cyprinus carpio) following exposure to tributyltin. Environmental Toxicology.31(3), 278–284.

*代表通讯作者,#代表共同第一。

Curriculum Vitae

First Name: Ping

Family Name: LI

Present position: Ph.D, Associate Professor, Master Supervisor

Address: Marine College, Shandong University, Weihai, No. 180, Wenhua West Road,Weihai,264209, P. R. China

Tel: 18963121036

Email: liping2018@email.sdu.edu.cn

Education:

2004, graduated from Life of Science (Bachelor degree), Shandong Normal University, China

2007, graduated from College of fishery (Master degree), Huazhong Agriculture University, China

2011, graduated from University of South Bohemia, Faculty of Fishery and Water Protection, Czech Republic. (Ph.D. thesis: Use of common carp (Cyprinus carpio L.) sperm to study the cryoinjuries induced by cryopreservation)

2012, as postdoc research fellow inDepartment of Biological Sciences, National University of Singapore; focus on the environment toxicology by biomonitoring of water quality using zebrafishwith transcriptome, proteome and metabolome approaches.

Professional experience:

2007.7-2018.4, Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan, Hubei, P R China

2018.5-till now, Marine College, Shandong University, Weihai, Shandong, P. R. China

Researchintroduction:

My major research topics are focusing on cryobiology, proteomics, cell biology and environmental biology. Up to now, I have published over 50 scientific papers in peer reviewed journals, inculding 19 papers by the first author (or corresponding author), and participated in 4 monographs in English or Chinese, and 3 patents for invention, and obtained 3 authorized invention patents.

Responsible leader of projects:

  • 31402301 Screening and functional analysis of protein markers of sperm quality in sturgeon (Projects supported by National Natural Science Foundation of China, 2015-2017, leader Ping Li)

  • GACR 16-02407Y Tf in the seminal plasma of carp and some sturgeons can help us to identify the role of proteins in the freezing of sperm (Projects supported by Czech Science Foundation 2016-2018, leader Ping Li),5985000CZK.

  • 2015B02YQ01 Mechanism and technology of reproductive regulation in aquatic organisms-Proliferation and cryopreservation of spermatogonial stem cells from Acipenser dabryanus (Projects supported by Special Scientific Research Fund for Central Non-profit Institutes, Chinese Academy of Fishery Sciences, 2015-2017, leader Ping Li)

  • 072/2008/P Ice-age endurance: difference expressions of sperm proteins before and after cryopreservation in teleost fishes (Projects supported by Grant agency of University of South Bohemia 2009, leaderPing Li)

  • 003/2010/Z Effect of cryopreservation on phosphorylation state of sperm proteins of common carp, Cyprinus carpio L. (Projects supported by Grant agency of University of South Bohemia 2010, leaderPing Li)

    Award:

    2010 -Chinese Government Award for Outstanding Self-Financed Students Abroad.

    2015-The third batch of "100 talents of science and technology training program" was selected by Chinese Academy of Fishery Sciences

    Referee for peer-reviewed journals:

PloS ONE; BioMed Research International; Reproduction, Fertility and Development; Fish Physiology and Biochemistry; Czech Journal of Animal Science etc.

Experience in other foreign laboratory:

2009 – Lab ofProf. Kazuo Inaba, Tsukuba University, Shimoda, Japan (40 days, proteomics technology )

List of publications in peer reviewed journals :

  1. Li P.,Guo W., Qiao X.M., Liu Z.G.,Shen L.,Wei Q.W.*,2018.Morphology and ultrastructure of Dabry’s sturgeon (Acipenser dabryanus) spermatozoa using scanning and transmission electron microscopy. Journal of Applied Ichthyology. Accepted.

  2. Xi M.D.#,Li P.#, Du H., Qiao X.M., Liu Z.G., Wei Q.W.*,2018.Disaccharidecombinations and theexpression ofenolase3 (ENO3) andplasmamembrane Ca2+ ATPaseisoform (PMCA2) insturgeonspermcryopreservation. Reproduction inDomesticAnimals.53: 472-483.

  3. Li P., Xi M.D., Du H., Qiao X.M., Liu Z.G., Wei Q.W.* 2018.Antioxidant supplementation, effect on post-thaw spermatozoon function in three sturgeon species.Reproduction in Domestic Animals.53: 287-295.

  4. Li P., Guo W., Yue H.M., Li C.J., Du H., Qiao X.M., Liu Z.G., Zhou Q., Wei Q.W. *.2017. Variability in the protein profiles in spermatozoa of two sturgeon species.PLoS One. 12(10): e0186003.

  5. Li, P.*, Hulak, M., Li, Z.H., Sulc, M., Psenicka, M., Rodina, M., Gela, D., Linhart., O., 2013.Cryopreservation of common carp (Cyprinus carpio L.) sperm induces protein phosphorylation in tyrosine and threonine residues.Theriogenology, 80(2): 84-89.

  6. Li, P.*, Li, Z.H.*, Hulak, M., Rodina, M., Linhart, O., 2012.Regulation of spermatozoa motility in response to cations in Russian sturgeon (Acipenser gueldenstaedtii). Theriogenology 78(1):102-109.

  7. Li, P.*, Rodina, M., Hulak, M., Li, Z.H., Linhart, O., 2011.Spermatozoa concentration, seminal plasma composition and their physiological relationship in the endangered stellate sturgeon (Acipenser stellatus) and Russian sturgeon (Acipenser gueldenstaedtii). Reproduction in Domestic Animals 46(2): 247-252.

  8. Li, P.*, Rodina, M., Hulak, M., Gela, D., Psenicka, M., Li, Z.H., Linhart, O., 2011.Physico-chemical properties and protein profiles of sperm from three freshwater chondrostean species: a comparative study among Siberian sturgeon (Acipenser baerii), sterlet (Acipenser ruthenus) and paddlefish (Polyodon spathula). Journal of Applied Ichthyology 27(2): 673-677.

  9. Li, P.*, Li, Z.H., Dzyuba, B., Hulak, M., Rodina, M., Linhart, O., 2010. Evaluating the impacts of osmotic and oxidative stress on common carp (Cyprinus carpio, L.) sperm caused by cryopreservation techniques.Biology of Reproduction 83(5): 852-858.

  10. Li, P.*, Dzyuba, B., Hulak, M., Rodina, M., Boryshpolets, S., Li, Z.H., Linhart, O., 2010. Percoll gradient separation of cryopreserved common carp spermatozoa to obtain a fraction with higher motility, velocity and membrane integrity. Theriogenology, 74(8): 1356-1361.

  11. Li, P.*, Hulak, M., Koubek, P., Sulc, M., Dzyuba, B., Boryshpolets, S., Rodina, M., Gela, D., Manaskova-Postlerova, P., Peknicova, J., Linhart., O., 2010. Ice-age endurance: the effects of cryopreservation on proteins of sperm of common carp,Cyprinus carpio L. Theriogenology 74(3): 413-423.

  12. Li, P.*, Hulak, M., Rodina, M., Sulc, M., Li, Z.H., Linhart, O., 2010.Comparative protein profiles: potential molecular markers from spermatozoa of Acipenseriformes (Chondrostei, Pisces).Comparative Biochemistry and Physiology: Part D: Genomics and Proteomics 5(4): 302-307.

  13. Li, P.*, Rodina, M., Hulak, M., Gela, D., Li, Z.H., Linhart, O., 2010.Physico-biochemical parameters and protein profiles of sperm from belugaHuso huso. Journal of Applied Ichthyology 26(5): 753-755.

  14. Li, P., Hulak, M., Linhart, O., 2009.Sperm proteins in teleostean and chondrostean (sturgeon) fishes. Fish Physiology and Biochemistry 35(4):567-581.

  15. Li, P., Wei, Q., Liu, L., 2008. DNA integrity of Polyodon spathula cryopreserved sperm. Journal of Applied Ichthyology 24(2): 121-125.

  16. Li, Z.H.*,Li, P.*, Sulc, M., Hulak, M., Randak, T.,2012.Hepatic proteome sensitivity in rainbow trout after chronically exposed to a human pharmaceutical Verapamil. Molecular and Cellular Proteomics, 11(1):M111.008409.

  17. Li P.& Li Z.H*. 2015. Physiological responses in Chinese rare minnow larvae following exposure to low-dose tributyltin. Bulletin of Environmental Contamination and Toxicology, 95:588–592.

  18. Li Z.H.*,Li P.*, Shi Z.C. 2015.Responses of the hepatic glutathione antioxidant defense system and related gene expression in juvenile common carp after chronic treatment with tributyltin. Ecotoxicology, 24, 700-705.

  19. Li Z.H.*,Li P.*, Shi Z.C. 2016. Chronic effects of tributyltin on multiple biomarkers responses in juvenile common carp,Cyprinus carpio. Environmental Toxicology. 31(8),937-944.

  20. Li Z.H.*,Li P.*, Shi Z.C. 2016.Physiological and molecular responses in brain of juvenile common carp (Cyprinus carpio) following exposure to tributyltin. Environmental Toxicology.31(3), 278–284.

    *corresponding author,#co-first author.


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山东大学(威海)海洋学院  地址:山东省威海市文化西路180号
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