周燕霞

2018年09月26日 09:52  点击:[]

227CD

周燕霞理学博士,副教授,硕士生导师

邮箱:zhouyx@sdu.edu.cn

研究方向:

(1)纳米药物和靶向给药系统;(2)海洋药用微生物资源及酶制剂开发;(3)肠道微生物与健康;(4)微生物污染评估和防控。

科研成果:

近年承担参与国家和省级项目9项,已发表SCI论文二十余篇,副主编著作《医药概论》。主持项目:

  1. 山东省山东省自然科学基金委员会,面上项目,海洋多糖介导抗耐药菌氧化锌纳米复合材料的绿色合成及构效关系研究,10万元,主持。

  2. 国家自然科学基金委员会, 青年项目, 基于刺参肠道宏基因组文库的新型高效褐藻胶降解酶的筛选及分子机制研究, 25万元,主持。

    (3)山东省自然科学基金委员会,面上项目,基于刺参肠道宏基因组文库的新型高效褐藻胶裂解酶的筛选和结构功能研究,17万元,主持。

    (4)中国博士后基金委员会,面上项目,一种双功能适冷外切褐藻胶裂解酶的表征及分子机制研究,5万元,主持。

    (5)校企共建实验项目,药剂生产环境菌群防控与新型检测技术开发,20万元,承担。

    (6)地方服务项目,应用于环境微生物检测的基因扩增仪可靠性分析,6万元,主持。

    共发表SCI论文30篇,代表论文:

    [1]Genetic and metabolic links between the murine microbiome and memory.Microbiome, 2020. (共一,IF15.5,Top)

    [2]Diverse tumour susceptibility in Collaborative Cross mice: identification of a new mouse model for human gastric tumourigenesis.Gut, 2019.(第四位,IF24.5,Top)

    [3]Insights into the Influence of Signal Peptide on the Enzymatic Properties of Alginate Lyase AlyI1 with Removal Effect onPseudomonas aeruginosaBiofilm,Marine Drugs, 2022.(通讯,IF6.1,Q1)

    [4]Preparation and characteristics of a thermosensitive in situ gel loaded with chitosan nanoparticles for optimal ocular delivery of chloramphenicol,Journal of Drug Delivery Science and Technology, 2023.(通讯,IF4.6, Q2)

    [5]Preliminary identification and semi-quantitative characterization of a multi-faceted high-stability alginate lyase from marine microbe Seonamhaeicola algicola with anti-biofilm effect onPseudomonas aeruginosa,Enzyme and Microbial Technology, 2024(通讯,IF3.4, Q2)

    [6]Characterization of a New Biofunctional, Exolytic AlginateLyase fromTamlanasp. s12 with High Catalytic Activity andCold-Adapted Features,Marine Drugs,2021.(通讯,IF5.4, Q1)

    [7]Skin permeation of curcumin nanocrystals: Effect of particle size, delivery vehicles, and permeation enhancer,Colloids and Surfaces B: Biointerfaces, 2023.(共通讯, IF 5.8, Q1)

    [8]Structure Characteristics, Biochemical Properties, and Pharmaceutical Applications of Alginate Lyases,Marine Drugs,2021.(通讯,IF5.4,Q1)

    [9]No difference in 4-nitroquinoline induced tumorigenesis between germ-free and colonized mice.Molecular Carcinogenesis, 2019. (一作,IF 3.8, Q2)

    [10]Thirdhand cigarette smoke leads to age-dependent and persistent alterations in the cecal microbiome of mice,MicrobiologyOpen, 2021. (共一,IF 3.14)

    [11]Pseudaestuariivita roseasp. nov., isolated fromAcmaea sp., a marine mollusk,Archives of Microbiology,2022.(通讯,IF 2.6)

    [12]Kangiella shandongensissp. nov., a novel species isolatedfrom saltern in Yantai, China,Antonie van Leeuwenhoek, 2021.(通讯,IF2.3)

    国家专利:

  3. 一种含氯霉素纳米粒的眼用温敏凝胶及其制备方法,2022

  4. 一种水溶性复方过硫酸氢钾消毒剂及其制备方法,2022

  5. 一种突变型褐藻胶裂解酶及其应用,2022

  6. 一种褐藻胶裂解酶AlyG2及其应用,2022

  7. 一种褐藻胶裂解酶ALyI1及其应用,2022

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