丛伟,农学博士,副教授,博士生导师,山东大学青年未来学者
办公地址:山东大学海洋学院515A办公室
邮箱:messicw@163.com; congwei2016@sdu.edu.cn
研究生招生专业:
硕士生:海洋科学(学术型)、生物与医药(专业型)
博士生:海洋科学(学术型)、资源与环境(专业型)
研究方向:
1.陆源性病原体陆海迁移机制研究:基于病原生物学、海洋科学、水动力学、环境科学等多学科领域交叉的研究思路和手段,探究以弓形虫为代表性的陆源性病原体的陆海迁移机制及生态风险评估,为制定相应的感染防控策略提供多元化的理论支撑。
2.噬菌体靶向防治海洋生物病害技术的开发及应用:利用噬菌体的专一性、高效性对海水养殖产业中的致病弧菌进行新型防控技术开发,将新型科技成果转化为现实可行的产品、技术,推动我国近海水产养殖业绿色发展。
主持的科研项目:
1.2024/01-2027/12国家自然科学基金面上项目:东亚江豚栖息地中陆源病原体弓形虫污染特征、迁移机制及生态风险研究,主持
2.2021/01-2025/12山东大学(威海)青年学者未来计划项目:弓形虫与宿主互作及抗弓形虫药物的筛选,主持
3.2018/01-2020/12国家自然科学基金青年基金项目:弓形虫卵囊对牡蛎感染机制的研究,主持
4.2020/01-2021/12山东省博士后创新项目一等资助:基于全基因组重测序及CRISPR-Cas9基因编辑技术筛选Nelfinavir抑制弓形虫增殖的药物靶点,主持
5.2019/01-2021/12山东省重点研发计划项目:HIV蛋白酶抑制类药物抗弓形虫效果及机制研究,主持
6.2019/01-2020/12中国博士后科学基金面上项目:基于LC-MS技术探究弓形虫感染对宿主代谢的影响,主持
7.2017/07-2018/12山东省自然科学基金项目:水生贝类软体动物源弓形虫虫株分离及其生物学特性研究,主持
8.2016/09-2018/12中国博士后科学基金面上项目:水生动物弓形虫病分子流行病学及生物学特性研究,主持
9.2017/09-2019/10家畜疫病病原生物学国家重点实验室开放基金项目:水生动物源弓形虫虫株分离及其生物学特性研究,主持
10.2023/02-2023/07横向课题:益生菌发酵红参关键技术开发,主持
11.2022/08-2023/12横向课题:荣成市外来入侵物种普查,主持
12.2023/05-2024/09横向课题:丹顶鹤等迁徙鸟类重要病原微生物检测技术开发,主持
发表论文:
以第一作者(或通讯)在Science of the Total Environment、Infectious Diseases of Poverty、Transboundary and Emerging Diseases等学术刊物发表60余篇,文章被引1300余次,H-index=21。
近三年代表性论文(*通讯作者):
Zuo MR, Li XT, Xu RZ, Sun WC*, Elsheikha HM*,Cong W*.Global prevalence and factors affecting the level ofCryptosporidiumcontamination in soil: A systematic review, meta-analysis, and meta-regression.Science of the Total Environment, 2023,891:164286.
Yang Q, Yang BT, Kang YH*,Cong W*.Efficacy of a recombinant Lactobacillus plantarum Lp-pPG-Malt as an oral vaccine candidate againstAeromonas hydrophilainfection in crucian carp. Fish & Shellfish Immunology, 2023, 136:108737.
Yang BT, Zhao T, Li HJ, Liang ZL,Cong W*, Kang YH*.Lc-pPG-612-OmpU-CTB: A promising oral vaccine for protectingCarassius auratusagainstVibrio mimicusinfection. Fish & Shellfish Immunology, 2023, 140:108973.
Ma JY, Zhu XK, Hu RG, Qi ZZ, Sun WC, Hao ZP,Cong W*, Kang YH*.A systematic review, meta-analysis and meta-regression of the global prevalence of foodborneVibriospp. infection in fishes: A persistent public health concern.Marine Pollution Bulletin,2023, 187:114521.
Li MY, Kang YH, Sun WC, Hao ZP, Elsheikha HM*,Cong W*.Terrestrial runoff influences the transport and contamination levels ofToxoplasma gondiiin marine organisms.Science of the Total Environment,2022, 851(Pt 1):158168.
Ma JY, Li MY, Qi ZZ, Fu M, Sun TF, Elsheikha HM*,Cong W*. Waterborne protozoan outbreaks: An update on the global, regional, and national prevalence from 2017 to 2020 and sources of contamination.Science of the Total Environment,2022, 806(Pt 2): 150562.
Nie LB,Cong W*, He JJ, Zheng WB,Zhu XQ*.Global proteomic profiling of multiple organs of cats (Felis catus) and proteome-transcriptome correlation during acuteToxoplasma gondiiinfection.Infectious Diseases of Poverty,2022, 11(1):96.
Lu D, Zhang NZ, Yao Y, Wang T, Hua Q, Zheng X,Cong W*, Tan F*.Investigation of Antiparasitic Activity of Two Marine Natural Products,Estradiol Benzoate, andOctyl Gallate, onToxoplasma gondiiInVitro.Frontiers in Pharmacology,2022, 13:841941.
Zhou CX*, Li LY, Huang CQ, Guo XD, An XD, Luo FF,Cong W*.Investigation of urine metabolome of BALB/c mouse infected with an avirulent strain ofToxoplasma gondii.Parasites &Vectors.2022,15(1):271.
Li MY, Gao XN, Ma JY, Elsheikha HM*,Cong W*. A systematic review, meta-analysis and meta-regression of the global prevalence ofToxoplasma gondiiinfection in wild marine mammals and associations with epidemiological variables.Transboundary and Emerging Diseases,2022, 69(5):e1213-e1230.
Cong W, Li MY, Zou Y, Ma JY, Wang B, Jiang ZY*,Elsheikha HM*. Prevalence, genotypes and risk factors forToxoplasma gondiicontamination in marine bivalve shellfish in offshore waters in eastern China.Ecotoxicology and Environmental Safety,2021, 213: 112048.
Cong W, Elsheikha HM*. Biology, Epidemiology, Clinical Features, Diagnosis, and Treatment of Selected Fish-borne Parasitic Zoonoses.Yale Journal of Biology and Medicine, 2021, 94:297-309.(Invited Review)
授权专利:
丛伟;王金磊;朱兴全;埃替格韦在制备抑制弓形虫生长的药物中的应用,2021-2-12,中国,ZL201910743699.3
丛伟;王金磊;朱兴全;替那拉韦在制备抑制弓形虫生长的药物中的应用,2021-1-19,中国,ZL201910743468.2
丛伟;王金磊:朱兴全:贝韦立马在制备抑制弓形虫生长的药物中的应用, 2022-2-28,中国,ZL201 910743473.3
学术兼职:
Frontiers in Cellular and Infection Microbiology客座编辑
Traditional Medicine Research青年编委
Decoding Infection & Transmission青年编委
Lancet Infectious Diseases, Food Research International,Infectious Diseases and Therapy,Transboundary and Emerging Diseases,Aquaculture,Fish & Shellfish Immunology,Vaccines, Parasites & Vectors等20余家学术期刊审稿人