苗晓庆

2020年03月14日 15:58  点击:[]

11DDB

姓名:苗晓庆

职称:副研究员

联系方式:miaoxiaoqing66@163.com

教育经历:

2012年9月-2016年8月 澳门大学 生物医药 哲学博士

2008年9月-2011年7月 沈阳药科大学 药剂学 理学硕士

2004年9月-2008年7月 哈尔滨医科大学 药学 理学学士

工作经历:

2019年9月-至今 山东大学(威海) 副研究员

2016年11月-2017年12月 深圳大学博士后

2011年7月-2012年7月 东阳光药业有限公司制剂研究员

研究方向:

1. 多功能纳米药物制剂设计及其克服口服吸收关键机制的研究

2. 高端创新制剂的转化研究

获奖情况:

2016年 深圳大学第三批优秀博士后入站奖励

2011年 沈阳药科大学优秀硕士毕业生

科研项目:

国家自然科学基金委员会,青年项目,51703132,双重靶向诊疗剂用于FL/MR/PA三模态成像指导的协同治疗研究,2018-01至2020-12,24万元,在研,参与

国家自然科学基金委员会,海外及港澳学者合作研究项目,2015CB932100,细胞和斑马鱼模型评价纳米制剂的跨膜转运机理和体内过程,2016-01至2019-12,18万元,已结题 ,参与

澳门科学技术发展基金委员会,FDCT Fund Project No: 044/2011/A2,中藥有效成分納米混懸給藥系統的研究,2015-01至2017-12,140万澳门币,已结题,参与

代表性论文:

第一作者论文

1.Xiaoqing Miao, Wuwei Yang, Tao Feng, Jing Lin, Peng Huang*, Drug nanocrystals for cancer therapy, Wiley Interdiscip Rev Nanomed Nanobiotechnol,10(3):e1499, 2018IF 6.5

Front Cover: Volume10, Issue3 May/June 2018. https://doi.org/10.1002/wnan.1525

Advanced Science News: https://www.advancedsciencenews.com/drug-nanocrystals-cancer-therapy/

2.Xiaoqing Miao, Ye Li, Xueqing Wang, Simon MY Lee, Ying Zheng*. Transport Mechanism of Coumarin 6 Nanocrystal in MDCKII Monolayer and Larval Zebrafish. ACS Applied Materials & Interfaces, 8:12620-12630, 2016IF: 8.1

3.Chao Bi1,Xiaoqing Miao1, Shing Fung Chow, Wenjin Wu, Ru Yan, AHL Chow*, Ying Zheng*. Particle Size Effect of Curcumin Nanosuspensions on Cytotoxicity, Cellular Internalization, in Vivo Pharmacokinetics and Biodistribution. Nanomedicine-Nanotechnology, Biology and Medicine, 13(3):943-953, 2016IF: 6.5

4.Xiaoqing Miao, Jing Zhou, Jian Li, Yonghong Liao*, Ying Zheng*. Chinese Medicine in Inhalation Therapy: a Review of Clinical Application and Formulation Development. Current Pharmaceutical Design, 21(27):3917-3931, 2015IF: 3.5

5.Xiaoqing Miao, Ye Li, Ian Wyman, Simon M. Y. Lee, Donal H. Macartney, Ying Zheng* and Ruibing Wang*. Enhanced in Vitro and in Vivo Uptake of a Hydrophobic Model Drug Coumarin-6 in the Presence of Cucurbit[7]Uril. Medical Chemical Communication, 6:1370-1374, 2015IF: 2.6

6.Xiaoqing Miao, Changshan Sun, Tongying Jiang, Li Zheng, Tianyi Wang, Siling Wang*. Investigation of Nanosized Crystalline Form to Improve the Oral Bioavailability of Poorly Water Soluble Cilostazol. Journal of Pharmacy and Pharmaceutical Sciences, 14:196-214, 2011IF: 2.0

非第一作者论文

1.Ye Li,Xiaoqing Miao, Tongkai Chen, Xiang Yi, Ruibing Wang, Haitao Zhao, Simon Ming-Yuen Lee, Xueqing Wang, Ying Zheng. Zebrafish as a Visual and Dynamic Model to Study the Transport of Nanosized Drug Delivery Systems across the Biological Barriers. Colloids and Surfaces B: Biointerfaces, 156: 227-235,2017 IF: 3.9

2.Li Shengke,Miao Xiaoqing, Wyman Ian W, Li Ye, Zheng Ying, Wang Yitao, Macartney Donal H, Wang Ruibing*. High-Affinity Host–Guest Complex of Cucurbit [7] Uril with a Bis (Thiazolium) Salt. Rsc Advances, 5: 56110-56115, 2015 IF: 3.8

3.Xiao Yang,Xiaoqing Miao, Fangrui Cao, Shang Li, Nana Ai, Qi Chang, Simon MY Lee, Ying Zheng*. Nanosuspension Development of Scutellarein as an Active and Rapidly Absorbed Precursor of Its Glycoside Scutellarin. Journal of Pharmaceutical Sciences, 103:3576-3584, 2014 IF: 3.0

4.Yancai Wang,Xiaoqing Miao, Lin Sun, Ju Song, Chao Bi, Xiao Yang, Ying Zheng*. Nanosuspension Formulations on Transport, Pharmacokinetics, in Vivo Targeting and Efficacy for Poorly Water-Soluble Drugs. Current Pharmaceutical Design, 20 (3) 454-473, 2013 IF: 3.5

5.Jian Li,Xiaoqing Miao, Tongkai Chen, Defang Ouyang, Ying Zheng* Preparation and Characterization of Pelletized Solid Dispersion of Resveratrol with Mesoporous Silica Microparticles to Improve Dissolution by Fluid-Bed Coating Techniques. Asian Journal of Pharmaceutical Science, 10 (7) 2534-2542, 2015. IF: 4.5

6. Ye Li; Tongkai Chen;Xiaoqing Miao; Xiang Yi; Xueqing Wang; Haitao Zhao; Simon Ming-Yuen Lee; Ying Zheng. Zebrafish: A promising in vivo model for assessing the delivery of natural products, fluorescence dyes and drugs across the blood-brain barrier.Pharmacological Research, 125(Part B): 246-257, 2017 IF 4.4

7.Chen Chen, Lisha Wang, Fangrui Cao,Xiaoqing Miao, Tongkai Chen, Qi Chang, Ying Zheng* Formulation of 20(S)-Protopanaxadiol Nanocrystals to Improve Oral Bioavailability and Brain Delivery. International Journal of Pharmaceutics, 497(1-2) 239-247. 2016 IF: 3.7

8.Yan Li, Shaoping Sun, Qi Chang, Lei Zhang, Gengnan Wang, Weixing Chen,Xiaoqing Miao, Ying Zheng*, A Novel Strategy on Improving Bioavailability and Anti-Osteoporosis Activity of BCS IV Flavonoids Glycoside by Formulation of Their Lipophilic Aglycone into Nanocrystals. Molecular Pharmaceutics, 10 (7), 2534-2542. 2013 IF: 4.6



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